Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.54 |
| ▸ | QPCT | Q16769 | 11/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 2/20 | 0.47 |
| ▸ | QPCTL | Q9NXS2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12332351 | 0.80 | PARP1 (0.57) | — | |
| SCHEMBL8634290 | 0.77 | QPCT (0.68) | BRD4CREBBPQPCTNPC1ALDH1A1 | |
| SCHEMBL3346625 | 0.77 | TERT (0.49) | QPCTNPC1ALDH1A1KDM4ETP53 | |
| SCHEMBL13680597 | 0.75 | ALDH1A1 (0.55) | NPC1ALDH1A1KDM4ETP53RAB9A | |
| SCHEMBL13680971 | 0.74 | TERT (0.44) | BRD4CREBBPQPCTNPC1ALDH1A1 | |
| SCHEMBL2457603 | 0.73 | QPCT (0.51) | BRD4CREBBPQPCTNPC1ALDH1A1 | |
| SCHEMBL2460276 | 0.73 | QPCT (0.51) | BRD4CREBBPQPCTNPC1ALDH1A1 | |
| SCHEMBL29458961 | 0.72 | QPCT (0.54) | BRD4CREBBPQPCTNPC1ALDH1A1 | |
| SCHEMBL19134465 | 0.72 | KDM4E (0.63) | QPCTNPC1ALDH1A1KDM4ETP53 | |
| SCHEMBL18551785 | 0.71 | BRD4 (0.50) | BRD4ALDH1A1KDM4EHPGDCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |