Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.44 |
| ▸ | QPCT | Q16769 | 13/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680972 | 0.78 | ALDH1A1 (0.45) | TERTKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL13680975 | 0.75 | PDE3B (0.48) | KDM4EALDH1A1TP53SMN1; SMN2HPGD | |
| SCHEMBL13680976 | 0.75 | MAPT (0.50) | TERTKDM4EALDH1A1TP53HPGD | |
| SCHEMBL13680996 | 0.74 | QPCT (0.44) | QPCTQPCTL | |
| SCHEMBL13680904 | 0.74 | NPC1 (0.45) | NPC1BRD4MAPT | |
| SCHEMBL13680596 | 0.74 | BRD4 (0.54) | TERTQPCTKDM4ENPC1ALDH1A1 | |
| SCHEMBL3346625 | 0.72 | TERT (0.49) | TERTQPCTKDM4ENPC1ALDH1A1 | |
| SCHEMBL13681029 | 0.71 | ALDH1A1 (0.36) | KDM4EALDH1A1SMN1; SMN2HPGDCYP1B1 | |
| SCHEMBL13681021 | 0.71 | HTR6 (0.33) | KDM4EALDH1A1SMN1; SMN2HPGDCYP3A4 | |
| SCHEMBL13680889 | 0.70 | ALDH1A1 (0.36) | KDM4EALDH1A1SMN1; SMN2HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |