Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680651 | 0.80 | IDO1 (0.47) | ENPP3IDO1METAP2RAB9AMAP4K4 | |
| SCHEMBL6885681 | 0.78 | RAB9A (0.54) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL13040 | 0.77 | MAP4K4 (0.66) | IDO1METAP2RAB9AMAP4K4ADORA1 | |
| SCHEMBL15344198 | 0.77 | EGLN1 (0.47) | IDO1METAP2RAB9AMAP4K4ACHE | |
| SCHEMBL13681263 | 0.76 | MAP4K4 (0.43) | ENPP3IDO1METAP2RAB9AMAP4K4 | |
| SCHEMBL13680652 | 0.76 | RAB9A (0.63) | IDO1METAP2RAB9AACHEBCHE | |
| SCHEMBL29373699 | 0.74 | ACHE (0.69) | ENPP3IDO1METAP2RAB9AMAP4K4 | |
| SCHEMBL31471473 | 0.74 | ACHE (0.69) | ENPP3IDO1METAP2RAB9AMAP4K4 | |
| SCHEMBL301247 | 0.74 | ACHE (0.69) | ENPP3IDO1METAP2RAB9AMAP4K4 | |
| SCHEMBL13680543 | 0.74 | FTO (0.50) | IDO1METAP2RAB9AMAP4K4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |