Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13606215 | 0.98 | AOC3 (0.52) | AOC3HTTDHFRSMN1; SMN2LMNA | |
| SCHEMBL4582036 | 0.86 | ADRB1 (0.54) | HTR1AHTR1DHTR2AHTR2CHTR7 | |
| SCHEMBL13680654 | 0.86 | AOC3 (0.54) | AOC3GRIN2BKDM4EALDH1A1HPGD | |
| SCHEMBL13606120 | 0.81 | CNR2 (0.43) | AOC3DHFRSMN1; SMN2LMNAGRIN2B | |
| SCHEMBL23601153 | 0.81 | CNR2 (0.58) | SMN1; SMN2LMNAKDM4E | |
| SCHEMBL13606217 | 0.79 | CNR2 (0.51) | AOC3DHFRSMN1; SMN2HTR1AHTR1D | |
| SCHEMBL13606218 | 0.79 | AOC3 (0.50) | AOC3DHFRALDH1A1NPC1RAB9A | |
| SCHEMBL2559530 | 0.79 | AOC3 (0.55) | AOC3DHFRGRIN2B | |
| SCHEMBL13606216 | 0.79 | KDM4E (0.56) | AOC3SMN1; SMN2HTR1AHTR7HTR2B | |
| SCHEMBL13606214 | 0.78 | NPC1 (0.54) | AOC3HTTSMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |