Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15344195 | 0.88 | FYN (0.53) | CNR2TLR9TLR8TLR7 | |
| SCHEMBL23601164 | 0.87 | KCNH2 (0.57) | CNR2TLR9TLR8TLR7 | |
| SCHEMBL23601163 | 0.83 | CNR2 (0.46) | CNR2TLR9TLR8TLR7ACHE | |
| SCHEMBL23601155 | 0.83 | DPP4 (0.63) | CNR2TLR8TLR7 | |
| SCHEMBL13680656 | 0.81 | AOC3 (0.51) | KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5232334 | 0.81 | CNR2 (0.57) | CNR2CNR1KDM4ETLR9TLR8 | |
| SCHEMBL24721357 | 0.81 | ATM (0.52) | CNR2CNR1KDM4ETLR9TLR8 | |
| SCHEMBL23601170 | 0.81 | CNR2 (0.50) | CNR2KDM4EACHEBACE1 | |
| SCHEMBL13606215 | 0.80 | AOC3 (0.52) | CNR2KDM4ELMNASMN1; SMN2 | |
| SCHEMBL23601161 | 0.80 | DPP4 (0.53) | CNR2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |