Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10348831 | 0.80 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2USP2TP53 | |
| SCHEMBL24359756 | 0.78 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10844089 | 0.78 | NPC1 (0.54) | RAB9ANPC1SMN1; SMN2USP2TP53 | |
| SCHEMBL10985177 | 0.75 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16826158 | 0.75 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL10842162 | 0.75 | NPC1 (0.59) | RAB9ANPC1SMN1; SMN2USP2TP53 | |
| SCHEMBL13680658 | 0.75 | BCHE (0.47) | RAB9ANPC1IDO1METAP2KDM1A | |
| SCHEMBL12759431 | 0.73 | KMO (0.39) | RAB9ANPC1SMN1; SMN2USP2TP53 | |
| SCHEMBL10842327 | 0.72 | SMN1; SMN2 (0.66) | RAB9ANPC1SMN1; SMN2USP2TP53 | |
| SCHEMBL8265012 | 0.72 | APP (0.50) | RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |