Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422110 | 0.86 | IDO1 (0.58) | BCHEACHEIDO1METAP2HSD17B1 | |
| SCHEMBL23601607 | 0.79 | KDM1A (0.53) | BCHEACHEIDO1METAP2HSD17B1 | |
| SCHEMBL8265012 | 0.78 | APP (0.50) | HSD17B1HSD17B2GRIN2BEGFRNPC1 | |
| SCHEMBL16826157 | 0.76 | KDM1A (0.50) | BCHEACHEIDO1METAP2HSD17B1 | |
| SCHEMBL13680659 | 0.75 | RAB9A (0.66) | IDO1METAP2KDM1AKMONISCH | |
| SCHEMBL23601695 | 0.73 | BCHE (0.47) | BCHEACHEIDO1METAP2HSD17B1 | |
| SCHEMBL23601693 | 0.73 | KDR (0.48) | BCHEACHEIDO1METAP2HSD17B1 | |
| SCHEMBL24636033 | 0.73 | BCHE (0.47) | BCHEACHEIDO1METAP2HSD17B1 | |
| SCHEMBL12973163 | 0.73 | HSD17B1 (0.59) | BCHEACHEIDO1METAP2HSD17B1 | |
| SCHEMBL12797772 | 0.73 | CYP3A4 (0.59) | BCHEACHEIDO1METAP2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |