Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.52 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.46 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 5/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680684 | 0.87 | HRH3 (0.46) | CNR2AOC3ALDH1A1POLB | |
| SCHEMBL23243798 | 0.83 | PIK3CA (0.52) | PIK3CAPIK3R1CNR2PIK3CDPIK3CB | |
| SCHEMBL13680685 | 0.83 | KCNH2 (0.49) | MAPTALDH1A1KCNH2 | |
| SCHEMBL24721063 | 0.82 | PIK3CA (0.49) | PIK3CAPIK3R1CNR2PIK3CDPIK3CB | |
| SCHEMBL1309697 | 0.79 | PIK3CA (0.52) | PIK3CAPIK3R1PIK3CDPIK3CBALDH1A1 | |
| SCHEMBL19496787 | 0.79 | AOC3 (0.51) | PIK3CAPIK3R1CNR2PIK3CDPIK3CB | |
| SCHEMBL13680654 | 0.75 | AOC3 (0.54) | PIK3CACNR2MAPTAOC3ALDH1A1 | |
| SCHEMBL15344111 | 0.75 | PIK3CA (0.53) | PIK3CAPIK3R1CNR2PIK3CDPIK3CB | |
| SCHEMBL18117983 | 0.75 | ALDH1A1 (0.53) | PIK3CAPIK3R1PIK3CDPIK3CBMAPT | |
| SCHEMBL12270084 | 0.72 | BRD9 (0.49) | CNR2PIK3CBMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |