Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680682 | 0.87 | PIK3CA (0.52) | CNR2ALDH1A1AOC3POLB | |
| SCHEMBL13680685 | 0.87 | KCNH2 (0.49) | CCR1CCR8CYP2A6ALDH1A1 | |
| SCHEMBL19626523 | 0.78 | CCR1 (0.48) | HRH3CCR1CCR8CYP2A6NPC1 | |
| SCHEMBL13680679 | 0.76 | CCR1 (0.60) | CCR1CCR8CYP2A6RAB9ATGFBR1 | |
| SCHEMBL16122790 | 0.76 | CNR2 (0.65) | HRH3CCR1CCR8CYP2A6CNR2 | |
| SCHEMBL12269941 | 0.75 | CAMK2D (0.47) | CCR1CCR8CYP2A6DHFR | |
| SCHEMBL13680656 | 0.73 | AOC3 (0.51) | NPC1ALDH1A1RAB9AAOC3SIGMAR1 | |
| SCHEMBL13680673 | 0.73 | CCR1 (0.56) | CCR1CCR8CYP2A6TGFBR1METAP2 | |
| SCHEMBL8241132 | 0.72 | ALDH1A1 (0.48) | NPC1ALDH1A1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL13606215 | 0.72 | AOC3 (0.52) | CNR2NPC1ALDH1A1RAB9AAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |