Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | HPGDS | O60760 | 11/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2199459 | 0.80 | PTGS1 (0.55) | SMN1; SMN2NPC1RAB9APTGS1PTGS2 | |
| SCHEMBL13680715 | 0.79 | TDP1 (0.42) | SMN1; SMN2NPC1RAB9APTGS1PTGS2 | |
| SCHEMBL8532336 | 0.77 | HPGD (0.52) | SMN1; SMN2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL13680718 | 0.76 | ALDH1A1 (0.39) | SMN1; SMN2NPC1RAB9APTGS1PTGS2 | |
| SCHEMBL13680711 | 0.76 | ALDH1A1 (0.39) | SMN1; SMN2NPC1RAB9APTGS1PTGS2 | |
| SCHEMBL18551805 | 0.75 | CYP1A2 (0.51) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL13680700 | 0.73 | MAP4K4 (0.41) | SMN1; SMN2NPC1RAB9APTGS1PTGS2 | |
| SCHEMBL13680709 | 0.73 | GRM5 (0.37) | SMN1; SMN2NPC1RAB9APTGS1PTGS2 | |
| SCHEMBL2317623 | 0.73 | ALOX15 (0.72) | SMN1; SMN2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL13680518 | 0.73 | MAPT (0.41) | SMN1; SMN2NPC1RAB9APTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |