Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680715 | 0.80 | TDP1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL13680702 | 0.78 | KDM4E (0.50) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL13680711 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL13680718 | 0.77 | ALDH1A1 (0.39) | MAP4K4ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13680716 | 0.76 | MAPT (0.39) | ALDH1A1KDM4EHPGDGAANPC1 | |
| SCHEMBL13680518 | 0.74 | MAPT (0.41) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL13680720 | 0.74 | GSK3B (0.38) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL13680709 | 0.74 | GRM5 (0.37) | GRM5ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13680469 | 0.73 | NPC1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL13680704 | 0.73 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EHPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |