Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680604 | 0.78 | GSK3B (0.42) | ALDH1A1HPGDSMN1; SMN2LMNAGSK3B | |
| SCHEMBL23197679 | 0.77 | TDP1 (0.56) | NQO2ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL13680452 | 0.77 | GSK3B (0.61) | NQO2ALDH1A1HPGDSMN1; SMN2GSK3B | |
| SCHEMBL17778297 | 0.76 | NQO2 (0.47) | NQO2ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL13681009 | 0.74 | ALDH1A1 (0.46) | NQO2ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL13680605 | 0.74 | HRH3 (0.50) | NQO2ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL8403545 | 0.74 | POLB (0.61) | ALDH1A1HPGDLMNAPOLBKMT2A | |
| SCHEMBL13680465 | 0.73 | GSK3B (0.61) | NQO2ALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL13680461 | 0.72 | SMN1; SMN2 (0.60) | NQO2ALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL13680520 | 0.72 | LMNA (0.53) | NQO2ALDH1A1HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |