Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680715 | 0.80 | TDP1 (0.42) | GSK3BNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL13680711 | 0.77 | ALDH1A1 (0.39) | GSK3BNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL13680718 | 0.77 | ALDH1A1 (0.39) | GSK3BNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL13681358 | 0.76 | ALDH1A1 (0.36) | GSK3BNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL13680700 | 0.74 | MAP4K4 (0.41) | GSK3BNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL13680518 | 0.74 | MAPT (0.41) | GSK3BNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL13680709 | 0.74 | GRM5 (0.37) | GSK3BNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL13680469 | 0.73 | NPC1 (0.42) | GSK3BNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL13680704 | 0.73 | SMN1; SMN2 (0.53) | NPC1ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL13681360 | 0.73 | ALDH1A1 (0.40) | NPC1ALDH1A1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |