Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680756 | 0.73 | PDE10A (0.46) | PDE10ATP53SMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL13681053 | 0.73 | RAB9A (0.37) | TP53SMN1; SMN2NPC1USP2PKM | |
| SCHEMBL13680575 | 0.72 | CYP2E1 (0.51) | PDE10AADORA2AADORA1CYP3A4CYP2E1 | |
| SCHEMBL10842162 | 0.70 | NPC1 (0.59) | TP53SMN1; SMN2NPC1USP2PKM | |
| SCHEMBL13680688 | 0.69 | CCR1 (0.57) | TP53SMN1; SMN2NPC1USP2PKM | |
| SCHEMBL13377800 | 0.69 | PDE10A (0.67) | PDE10ATP53SMN1; SMN2RAB9AADORA2A | |
| SCHEMBL18157874 | 0.69 | SMN1; SMN2 (0.55) | PDE10ATP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4278637 | 0.68 | NPC1 (0.58) | TP53SMN1; SMN2NPC1USP2PKM | |
| SCHEMBL2629425 | 0.67 | RAB9A (0.48) | TP53SMN1; SMN2NPC1USP2PKM | |
| SCHEMBL10842285 | 0.66 | SMN1; SMN2 (0.69) | TP53SMN1; SMN2NPC1USP2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |