Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.56 |
| ▸ | KIF11 | P52732 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 5/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18003547 | 0.89 | MAOB (0.50) | AGXTKIF11MAOBPTPN5TAAR1 | |
| SCHEMBL11932723 | 0.84 | MAOB (0.58) | KIF11MAOBTAAR1 | |
| SCHEMBL66607 | 0.82 | TAAR1 (0.61) | TAAR1 | |
| SCHEMBL418611 | 0.82 | GPR52 (0.50) | AGXTFFAR1 | |
| SCHEMBL13680786 | 0.81 | CHRM2 (0.46) | AGXTSLC13A5 | |
| SCHEMBL27962427 | 0.80 | AGXT (0.60) | AGXTKIF11MAOBPTPN5MGLL | |
| SCHEMBL13182829 | 0.80 | AGXT (0.60) | AGXTKIF11MAOBPTPN5MGLL | |
| SCHEMBL2652456 | 0.80 | AGXT (0.60) | AGXTKIF11MAOBPTPN5MGLL | |
| Formaldehyde SCHEMBL28263667 | 0.80 | TAAR1 (0.57) | TAAR1 | |
| SCHEMBL8413593 | 0.80 | TAAR1 (0.44) | AGXTMAOBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |