Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CEL | P19835 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CTRC | Q99895 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1616548 | 0.84 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPTPOLBPKM | |
| SCHEMBL8649236 | 0.75 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPTKDM4EPOLB | |
| SCHEMBL4155788 | 0.75 | CHRM2 (0.45) | ALDH1A1TSHRMAPTKDM4EPOLB | |
| SCHEMBL13680861 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL28772965 | 0.75 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL13680864 | 0.74 | ALDH1A1 (0.63) | ALDH1A1TSHRMAPTKDM4EPOLB | |
| SCHEMBL25183771 | 0.71 | HIF1A (0.41) | ALDH1A1TSHR | |
| SCHEMBL3350886 | 0.71 | — | — | |
| SCHEMBL12820167 | 0.71 | — | — | |
| SCHEMBL13680865 | 0.71 | SOS1 (0.56) | ALDH1A1MAPTKDM4EPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |