Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680898 | 0.85 | MAPK1 (0.43) | ALDH1A1KDM4EMAPTPKMHPGD | |
| SCHEMBL13680889 | 0.80 | ALDH1A1 (0.36) | ALDH1A1KDM4EMAPTPKMHPGD | |
| SCHEMBL13680899 | 0.80 | CYP2C19 (0.40) | ALDH1A1KDM4EMAPTPKMHPGD | |
| SCHEMBL20339667 | 0.79 | KDM4E (0.60) | ALDH1A1KDM4EMAPTHPGDCYP2C19 | |
| SCHEMBL13680882 | 0.79 | KDM4E (0.60) | ALDH1A1KDM4EMAPTPKMHPGD | |
| SCHEMBL13681005 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTPKMHPGD | |
| SCHEMBL13681294 | 0.76 | ALDH1A1 (0.33) | ALDH1A1KDM4EMAPTPKMHPGD | |
| SCHEMBL13680885 | 0.76 | TRPV4 (0.35) | ALDH1A1KDM4EMAPTPKMHPGD | |
| SCHEMBL13680902 | 0.76 | APP (0.40) | ALDH1A1KDM4EMAPTPKMHPGD | |
| SCHEMBL13680900 | 0.76 | MAPT (0.41) | ALDH1A1KDM4EMAPTPKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |