Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680903 | 0.84 | ALDH1A1 (0.40) | MAPTKDM4EALDH1A1PKMCYP2A6 | |
| SCHEMBL13680901 | 0.84 | CYP1A2 (0.36) | MAPTKDM4EALDH1A1PKMHDAC6 | |
| SCHEMBL13680899 | 0.82 | CYP2C19 (0.40) | MAPTKDM4EALDH1A1PKMCYP2A6 | |
| SCHEMBL13680898 | 0.80 | MAPK1 (0.43) | MAPTKDM4EALDH1A1PKMNPC1 | |
| SCHEMBL13680889 | 0.80 | ALDH1A1 (0.36) | MAPTKDM4EALDH1A1PKMCYP2A6 | |
| SCHEMBL13681006 | 0.79 | CYP2C19 (0.39) | MAPTKDM4EALDH1A1PKMNPC1 | |
| SCHEMBL13680867 | 0.79 | ALDH1A1 (0.63) | MAPTKDM4EALDH1A1PKMALOX5 | |
| SCHEMBL13680902 | 0.79 | APP (0.40) | MAPTKDM4EALDH1A1PKMNPC1 | |
| SCHEMBL13681294 | 0.76 | ALDH1A1 (0.33) | MAPTKDM4EALDH1A1PKMCYP2A6 | |
| SCHEMBL13680896 | 0.76 | ALDH1A1 (0.41) | MAPTKDM4EALDH1A1PKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |