Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680866 | 0.80 | ALDH1A1 (0.60) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL13680887 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL13680881 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL13680979 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL13680864 | 0.77 | ALDH1A1 (0.63) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL13680999 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL13680859 | 0.77 | ALDH1A1 (0.60) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL13680867 | 0.77 | ALDH1A1 (0.63) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL13680882 | 0.77 | KDM4E (0.60) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL13681009 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |