Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680927 | 0.84 | LMNA (0.45) | DRD2DRD4DRD3LMNAHDAC1 | |
| SCHEMBL12844627 | 0.78 | DRD2 (0.51) | DRD2DRD4DRD3FFAR1ALDH1A1 | |
| SCHEMBL5541970 | 0.78 | DRD2 (0.55) | DRD2DRD4DRD3FFAR1ALDH1A1 | |
| SCHEMBL5106193 | 0.78 | DRD2 (0.51) | DRD2DRD4DRD3FFAR1ALDH1A1 | |
| SCHEMBL2225947 | 0.78 | DRD2 (0.51) | DRD2DRD4DRD3FFAR1ALDH1A1 | |
| SCHEMBL13680924 | 0.78 | SCN10A (0.44) | FFAR1LMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL6593764 | 0.78 | DRD2 (0.54) | DRD2DRD4DRD3FFAR1ALDH1A1 | |
| SCHEMBL5543626 | 0.75 | DRD2 (0.49) | DRD2DRD4DRD3FFAR1ALDH1A1 | |
| SCHEMBL26525864 | 0.75 | DRD2 (0.49) | DRD2DRD4DRD3FFAR1ALDH1A1 | |
| SCHEMBL27682910 | 0.75 | DRD2 (0.49) | DRD2DRD4DRD3FFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |