Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 6/20 | 0.70 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.70 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.70 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.70 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12611015 | 0.86 | CHRM1 (0.83) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL1039720 | 0.83 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL5281450 | 0.83 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL1039722 | 0.83 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL20838572 | 0.83 | SLC1A2 (1.00) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL2491997 | 0.82 | CHRM1 (0.68) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL23565818 | 0.80 | SLC1A2 (0.67) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL2386631 | 0.80 | CHRM1 (0.65) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL8939043 | 0.80 | CHRM1 (0.65) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL27749943 | 0.80 | CHRM1 (0.65) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114828841-A | Use of valproic acid for reducing post-operative scarring after glaucoma surgery | 参天制药株式会社 | 2022-07-29 | — | — | CN | claimed |
| US-20230058189-A1 | QUINOLIN-4-ONE AND 4(1H)-CINNOLINONE COMPOUNDS AND METHODS OF USING SAME | Frequency Therapeutics, Inc. (US) | 2023-02-23 | — | — | US | disclosed |
| US-20230015595-A1 | USE OF VALPROIC ACID FOR REDUCING POST-OPERATIVE SCARRING FOLLOWING A GLAUCOMA SURGERY | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | US | disclosed |
| CN-114828841-A | Use of valproic acid for reducing post-operative scarring after glaucoma surgery | 参天制药株式会社 | 2022-07-29 | — | — | CN | disclosed |
| US-20220096639-A1 | THERMOREVERSIBLE COMPOSITIONS FOR ADMINISTRATION OF THERAPEUTIC AGENTS | Frequency Therapeutics, Inc. | 2022-03-31 | — | — | US | disclosed |
| EP-3921309-A1 | QUINOLIN-4-ONE AND 4(1H)-CINNOLINONE COMPOUNDS AND METHODS OF USING SAME | Frequency Therapeutics, Inc. (US) | 2021-12-15 | — | — | EP | disclosed |
| US-11160868-B2 | Thermoreversible compositions for administration of therapeutic agents | Frequency Therapeutics, Inc. (US) | 2021-11-02 | — | — | US | disclosed |
| US-20210300948-A1 | 1H-PYRROLE-2,5-DIONE COMPOUNDS AND METHODS OF USING THEM TO INDUCE SELF-RENEWAL OF STEM/PROGENITOR SUPPORTING CELLS | Frequency Therapeutics, Inc. | 2021-09-30 | — | — | US | disclosed |
| US-11066419-B2 | 1H-pyrrole-2,5-dione compounds and methods of using same | Frequency Therapeutics, Inc. (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200316089-A1 | 1,2-DIHYDRO-3H-PYRAZOL-3-ONE COMPOUNDS AND METHODS OF USING SAME | Frequency Therapeutics, Inc. | 2020-10-08 | — | — | US | disclosed |
| US-20130237602-A1 | VALPROIC ACID DRUG DELIVERY SYSTEMS AND INTRAOCULAR THERAPEUTIC USES THEREOF | ALLERGAN, INC. (US) | 2013-09-12 | — | — | US | disclosed |
| EP-2395970-B1 | VALPROIC ACID DRUG DELIVERY SYSTEMS AND INTRAOCULAR THERAPEUTIC USES THEREOF | ALLERGAN INC (US) | 2013-04-17 | — | — | EP | disclosed |
| EP-1719768-B1 | NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS | ASAHI KASEI PHARMA CORP (JP) | 2012-04-25 | — | — | EP | disclosed |
| US-20120059060-A1 | VALPROIC ACID DRUG DELIVERY SYSTEMS AND INTRAOCULAR THERAPEUTIC USES THEREOF | ALLERGAN, INC. | 2012-03-08 | — | — | US | disclosed |
| US-20120015925-A1 | NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
| US-7973030-B2 | Benzothiazepine and benzothiepine compounds | ASAHI KASEI PHARMA CORPORATION (JP) | 2011-07-05 | — | — | US | disclosed |
| WO-2010093564-A1 | VALPROIC ACID DRUG DELIVERY SYSTEMS AND INTRAOCULAR THERAPEUTIC USES THEREOF | ALLERGAN, INC. (US) | 2010-08-19 | — | — | WO | disclosed |
| US-20100204325-A1 | VALPROIC ACID DRUG DELIVERY SYSTEMS AND INTRAOCULAR THERAPEUTIC USES THEREOF | ALLERGAN, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-20070190041-A1 | Novel benzothiazepine and bensothiepine compounds | ASHAI KASEI PHARAMA CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1719768-A1 | NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS | Asahi Kasei Pharma Corporation (JP) | 2006-11-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11160868-B2 | Thermoreversible compositions for administration of therapeutic agents | MKI67, MCL1, HSPE1 | SLC1A2 3659/4885SLC1A1 3448/4885SLC1A3 3753/4885 |
| US-20210300948-A1 | 1H-PYRROLE-2,5-DIONE COMPOUNDS AND METHODS OF USING THEM TO INDUCE SELF-RENEWAL OF STEM/PROGENITOR SUPPORTING CELLS | MCL1, PROX1, MKI67 | SLC1A2 3297/4885SLC1A1 3158/4885SLC1A3 3681/4885 |
| US-20220096639-A1 | THERMOREVERSIBLE COMPOSITIONS FOR ADMINISTRATION OF THERAPEUTIC AGENTS | MKI67, MCL1, HSPE1 | SLC1A2 3659/4885SLC1A1 3448/4885SLC1A3 3753/4885 |
| US-20200316089-A1 | 1,2-DIHYDRO-3H-PYRAZOL-3-ONE COMPOUNDS AND METHODS OF USING SAME | DCX, MCL1, MKI67 | SLC1A2 3766/4885SLC1A1 3372/4885SLC1A3 3580/4885 |
| US-20230058189-A1 | QUINOLIN-4-ONE AND 4(1H)-CINNOLINONE COMPOUNDS AND METHODS OF USING SAME | DCX, NES, MCL1 | SLC1A2 2760/4885SLC1A1 2180/4885SLC1A3 3360/4885 |
| US-20120015925-A1 | NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS | SLC10A1, SREBF1, SPTLC1 | SLC1A2 562/4885SLC1A1 432/4885SLC1A3 599/4885 |
| US-11066419-B2 | 1H-pyrrole-2,5-dione compounds and methods of using same | MKI67, PROX1, DCX | SLC1A2 3531/4885SLC1A1 3543/4885SLC1A3 4018/4885 |
| US-20070190041-A1 | Novel benzothiazepine and bensothiepine compounds | SLC10A1, GOT1, CES1 | SLC1A2 390/4885SLC1A1 246/4885SLC1A3 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.