Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL262332 | 0.80 | MEN1 (0.41) | MEN1KMT2AALDH1A1CYP1A2KDM4E | |
| SCHEMBL3648376 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1CYP1A2KDM4E | |
| SCHEMBL5000471 | 0.76 | KDM4E (0.48) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL2560578 | 0.75 | SCN4A (0.47) | KMT2AALDH1A1CYP1A2KDM4ECYP2D6 | |
| SCHEMBL941531 | 0.74 | KMT2A (0.45) | MEN1KMT2AALDH1A1CYP1A2KDM4E | |
| SCHEMBL27733271 | 0.72 | MEN1 (0.44) | MEN1KMT2AALDH1A1CYP1A2KDM4E | |
| SCHEMBL3355925 | 0.72 | MEN1 (0.45) | MEN1KMT2AALDH1A1CYP1A2KDM4E | |
| SCHEMBL13662461 | 0.72 | — | — | |
| SCHEMBL13964533 | 0.72 | LMNA (0.43) | MEN1KMT2AALDH1A1CYP1A2KDM4E | |
| SCHEMBL20904927 | 0.72 | POLB (0.33) | KMT2AALDH1A1KDM4EPOLBTUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592331-B2 | Macrocyclic factor VIIa inhibitors useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-09-22 | — | — | US | disclosed |