Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | CSK | P41240 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3865771 | 0.83 | ENPP2 (0.44) | LPLLIPGMGLLENPP2CXCR1 | |
| SCHEMBL5662615 | 0.80 | LOXL2 (0.35) | KDM4ECA2CA1 | |
| SCHEMBL643420 | 0.80 | MAPT (0.38) | — | |
| SCHEMBL5780510 | 0.80 | ALDH1A1 (0.38) | — | |
| SCHEMBL7763429 | 0.79 | MEN1 (0.41) | — | |
| SCHEMBL11503093 | 0.79 | RXRA (0.41) | KDM4ECA2 | |
| SCHEMBL5603701 | 0.79 | ALDH1A1 (0.43) | — | |
| SCHEMBL6376616 | 0.78 | PPARA (0.44) | CA2 | |
| SCHEMBL403826 | 0.77 | TAAR1 (0.47) | — | |
| SCHEMBL6370660 | 0.77 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020207352-A1 | TRIAZINE BENZIMIDAZOLE COMPOUNDS AND MEDICAL USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2020-10-15 | — | — | WO | disclosed |
| EP-1924561-B1 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | LILLY CO ELI (US) | 2012-11-14 | — | — | EP | disclosed |