Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | EDNRB | P24530 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319456 | 0.85 | AKR1C3 (0.50) | LMNANPC1RAB9ASMN1; SMN2PDK1 | |
| SCHEMBL2797715 | 0.84 | CES2 (0.50) | CES2CES1LMNAPARP1NPC1 | |
| SCHEMBL4958167 | 0.84 | CES2 (0.50) | CES2CES1LMNAPARP1NPC1 | |
| SCHEMBL1356271 | 0.84 | AKR1C3 (0.52) | CES2CES1LMNAPARP1NPC1 | |
| SCHEMBL28036447 | 0.84 | NPC1 (0.44) | CES2CES1LMNAPARP1NPC1 | |
| SCHEMBL6288739 | 0.83 | CES2 (0.49) | CES2CES1LMNAPARP1NPC1 | |
| SCHEMBL4693833 | 0.83 | CES2 (0.49) | CES2CES1LMNAPARP1NPC1 | |
| SCHEMBL7332434 | 0.81 | KDM4E (0.53) | KDM4ECYP1A2TSHR | |
| SCHEMBL30577887 | 0.81 | KDM4E (0.53) | KDM4ECYP1A2TSHR | |
| SCHEMBL14166571 | 0.81 | CYP2C9 (0.49) | CES2CES1LMNAPARP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110287059-A1 | HONEY ANALYSIS | COMVITA NEW ZEALAND LIMITED (NZ) | 2011-11-24 | — | — | US | disclosed |
| EP-2368111-A1 | HONEY ANALYSIS | Comvita New Zealand Limited (NZ) | 2011-09-28 | — | — | EP | disclosed |
| WO-2010082845-A1 | HONEY ANALYSIS | COMVITA NEW ZEALAND LIMITED (NZ) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287059-A1 | HONEY ANALYSIS | GLO1, GLMN, AGER | CES2 4015/4885CES1 4402/4885LMNA 2071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.