Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1587040 | 1.00 | CYP1A2 (0.51) | CYP1A2CYP1A1CYP1B1CA12CA9 | |
| SCHEMBL16318865 | 0.89 | MAOB (0.48) | CYP1A2CA12CA9CA1CA2 | |
| SCHEMBL2135232 | 0.89 | MAOB (0.48) | CYP1A2CA12CA9CA1CA2 | |
| SCHEMBL19972316 | 0.85 | CA12 (0.57) | CYP1A2CYP1A1CYP1B1CA12CA9 | |
| SCHEMBL14272842 | 0.85 | CA12 (0.57) | CYP1A2CYP1A1CYP1B1CA12CA9 | |
| SCHEMBL435330 | 0.84 | MAOB (0.49) | CYP1A2CA12CA9CA1CA2 | |
| SCHEMBL18538452 | 0.84 | MAOB (0.56) | CYP1A2CYP1A1CYP1B1CA12CA9 | |
| SCHEMBL4592398 | 0.84 | MAPT (0.68) | CYP1A2CYP1A1CYP1B1MAOBALDH1A1 | |
| SCHEMBL4592405 | 0.84 | MAPT (0.68) | CYP1A2CYP1A1CYP1B1MAOBALDH1A1 | |
| SCHEMBL28139586 | 0.84 | MAOB (0.56) | CYP1A2CYP1A1CYP1B1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914580-B1 | THIOARYL DERIVATIVES AS GPR120 AGONISTS | LG CHEMICAL LTD (KR) | 2019-02-20 | — | — | EP | disclosed |
| US-9447044-B2 | Thioaryl derivatives as GPR120 agonists | LG LIFE SCIENCES LTD. (KR) | 2016-09-20 | — | — | US | disclosed |
| US-20150291527-A1 | THIOARYL DERIVATIVES AS GPR120 AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2015-10-15 | — | — | US | disclosed |
| EP-2914580-A1 | THIOARYL DERIVATIVES AS GPR120 AGONISTS | LG Life Sciences Ltd. (KR) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014069963-A1 | THIOARYL DERIVATIVES AS GPR120 AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2014-05-08 | — | — | WO | disclosed |
| US-7585880-B2 | Phenylpropanoic acid derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-08 | — | — | US | disclosed |
| US-20070155808-A1 | Phenylpropanoic acid derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291527-A1 | THIOARYL DERIVATIVES AS GPR120 AGONISTS | GPR119, GLP1R, GCGR | CYP1A2 715/4885CYP1A1 761/4885CYP1B1 919/4885 |
| US-20070155808-A1 | Phenylpropanoic acid derivatives | GPR119, GPR55, FFAR1 | CYP1A2 2051/4885CYP1A1 771/4885CYP1B1 1208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.