⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3819537 | 0.73 | KDM4E (0.38) | — | |
| SCHEMBL18529056 | 0.71 | PKM (0.43) | — | |
| SCHEMBL29511790 | 0.54 | HSD17B10 (0.33) | — | |
| SCHEMBL18529006 | 0.54 | HSD17B10 (0.33) | — | |
| SCHEMBL13349383 | 0.51 | — | — | |
| SCHEMBL29164347 | 0.51 | JAK2 (0.31) | — | |
| SCHEMBL13226766 | 0.51 | ALDH1A1 (0.42) | — | |
| SCHEMBL2556110 | 0.49 | L3MBTL1 (0.36) | — | |
| SCHEMBL1300155 | 0.48 | JAK2 (0.41) | — | |
| SCHEMBL12948529 | 0.45 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595320-B2 | Hydrazinocarbonyl-thieno[2,3-C]pyrazoles, process for preparing them, compositions containing them and use thereof | AVENTIS PHARMA S.A. (FR) | 2009-09-29 | — | — | US | disclosed |
| US-20080146542-A1 | Hydrazinocarbonyl-thieno[2,3-C]pyrazoles, Process for Preparing Them, Compositions Containing Them and Use Thereof | AVENTIS PHARMA S.A. (FR) | 2008-06-19 | — | — | US | disclosed |