Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | PTAFR | P25105 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | PLD2 | O14939 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188836 | 0.81 | NPC1 (0.46) | OPRM1TMEM97SIGMAR1DRD4NPC1 | |
| SCHEMBL13691772 | 0.80 | OPRM1 (0.46) | OPRM1TMEM97SIGMAR1DRD4NPC1 | |
| SCHEMBL13691769 | 0.79 | OPRM1 (0.46) | OPRM1TMEM97SIGMAR1DRD4NPC1 | |
| SCHEMBL13689401 | 0.78 | OPRM1 (0.45) | OPRM1TMEM97SIGMAR1DRD4NPC1 | |
| SCHEMBL13689398 | 0.77 | NPC1 (0.44) | OPRM1TMEM97SIGMAR1NAMPTDRD4 | |
| SCHEMBL13691768 | 0.76 | OPRM1 (0.45) | OPRM1TMEM97SIGMAR1NPC1RAB9A | |
| SCHEMBL13691797 | 0.76 | DRD2 (0.54) | OPRM1TMEM97SIGMAR1DRD4CYP2C19 | |
| SCHEMBL13689397 | 0.74 | CXCR4 (0.43) | OPRM1TMEM97SIGMAR1DRD4NPC1 | |
| SCHEMBL13188839 | 0.72 | TMEM97 (0.42) | OPRM1TMEM97SIGMAR1DRD4EPHX2 | |
| SCHEMBL13691793 | 0.69 | NPC1 (0.47) | OPRM1TMEM97SIGMAR1DRD4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105824-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC5 RECEPTOR AND TREATMENT OF CONDITIONS RELATED TO THIS RECEPTOR | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |