Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691793 | 0.84 | NPC1 (0.47) | NPC1OPRM1RAB9AOPRD1SMN1; SMN2 | |
| SCHEMBL13689520 | 0.78 | DRD3 (0.49) | NPC1DRD4 | |
| SCHEMBL13689525 | 0.78 | DRD3 (0.51) | NPC1DRD4 | |
| SCHEMBL13689396 | 0.77 | OPRM1 (0.45) | NPC1OPRM1RAB9ASMN1; SMN2TMEM97 | |
| SCHEMBL13691762 | 0.76 | NPC1 (0.44) | NPC1OPRM1RAB9AOPRD1SMN1; SMN2 | |
| SCHEMBL13190966 | 0.73 | HPGD (0.47) | NPC1OPRM1RAB9AOPRD1SMN1; SMN2 | |
| SCHEMBL13691761 | 0.72 | DRD3 (0.43) | NPC1OPRM1RAB9AOPRD1SMN1; SMN2 | |
| SCHEMBL13188836 | 0.71 | NPC1 (0.46) | NPC1OPRM1RAB9AOPRD1SMN1; SMN2 | |
| SCHEMBL13691769 | 0.71 | OPRM1 (0.46) | NPC1OPRM1RAB9AOPRD1SMN1; SMN2 | |
| SCHEMBL13689401 | 0.70 | OPRM1 (0.45) | NPC1OPRM1RAB9ASMN1; SMN2TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105824-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC5 RECEPTOR AND TREATMENT OF CONDITIONS RELATED TO THIS RECEPTOR | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |