Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 9/20 | 0.49 |
| ▸ | DRD2 | P14416 | 9/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | MC5R | P33032 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | MC1R | Q01726 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13689525 | 0.98 | DRD3 (0.51) | DRD3DRD2MC4RMC5RMC3R | |
| SCHEMBL13691800 | 0.89 | OPRK1 (0.49) | — | |
| SCHEMBL13691797 | 0.87 | DRD2 (0.54) | DRD3DRD2MC4RMC5RMC3R | |
| SCHEMBL13691761 | 0.87 | DRD3 (0.43) | DRD3DRD2MC4RMC5RMC3R | |
| SCHEMBL13691793 | 0.85 | NPC1 (0.47) | DRD3DRD2NPC1DRD4 | |
| SCHEMBL13691795 | 0.80 | DRD3 (0.47) | DRD3DRD2MC4RMC5RMC3R | |
| SCHEMBL13689398 | 0.78 | NPC1 (0.44) | NPC1DRD4 | |
| SCHEMBL13691762 | 0.77 | NPC1 (0.44) | DRD3DRD2NPC1DRD4 | |
| SCHEMBL13188833 | 0.77 | DRD2 (0.46) | DRD3DRD2MC4RMC5RMC3R | |
| SCHEMBL13689526 | 0.76 | SMYD2 (0.45) | DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105824-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC5 RECEPTOR AND TREATMENT OF CONDITIONS RELATED TO THIS RECEPTOR | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |