Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.47 |
| ▸ | DRD2 | P14416 | 7/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MC5R | P33032 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | MC1R | Q01726 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188833 | 0.95 | DRD2 (0.46) | DRD3DRD2MC4RMC5RMC3R | |
| SCHEMBL13691770 | 0.90 | MC4R (0.47) | DRD3DRD2MC4RMC5RMC3R | |
| SCHEMBL13689531 | 0.87 | DRD3 (0.52) | DRD3DRD2HSP90AA1ALOX5PYGL | |
| SCHEMBL13190970 | 0.82 | DRD2 (0.51) | DRD3DRD2MC4RMC5RMC3R | |
| SCHEMBL13691792 | 0.81 | DRD2 (0.52) | DRD3DRD2MC4RMC5RMC3R | |
| SCHEMBL13689522 | 0.80 | DRD2 (0.49) | DRD3DRD2MC4RMC5RMC3R | |
| SCHEMBL13689520 | 0.80 | DRD3 (0.49) | DRD3DRD2MC4RMC5RMC3R | |
| SCHEMBL13689525 | 0.78 | DRD3 (0.51) | DRD3DRD2MC4RMC5RMC3R | |
| SCHEMBL13691865 | 0.76 | MC4R (0.43) | DRD3DRD2HSP90AA1MC4RMC5R | |
| SCHEMBL13190971 | 0.73 | MC4R (0.48) | DRD3DRD2MC4RMC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105823-A1 | 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |