Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.44 |
| ▸ | DRD3 | P35462 | 6/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AHCY | P23526 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | MC1R | Q01726 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691778 | 1.00 | DRD2 (0.44) | DRD2DRD3HTR1AUTS2RSLC6A4 | |
| SCHEMBL19474295 | 1.00 | DRD2 (0.44) | DRD2DRD3HTR1AUTS2RSLC6A4 | |
| SCHEMBL13691779 | 1.00 | DRD2 (0.44) | DRD2DRD3HTR1AUTS2RSLC6A4 | |
| SCHEMBL13188483 | 1.00 | DRD2 (0.44) | DRD2DRD3HTR1AUTS2RSLC6A4 | |
| SCHEMBL19474294 | 0.94 | DRD2 (0.43) | DRD2DRD3HTR1AUTS2RSLC6A4 | |
| SCHEMBL19474293 | 0.94 | DRD2 (0.43) | DRD2DRD3HTR1AUTS2RSLC6A4 | |
| SCHEMBL15372756 | 0.93 | DRD2 (0.42) | DRD2DRD3HTR1AUTS2RSLC6A4 | |
| SCHEMBL13691855 | 0.92 | DRD2 (0.45) | DRD2DRD3HTR1AUTS2RSLC6A4 | |
| SCHEMBL13691857 | 0.91 | DRD2 (0.45) | DRD2DRD3HTR1AUTS2RSLC6A4 | |
| SCHEMBL13691859 | 0.84 | OPRK1 (0.43) | DRD2DRD3HTR1ASLC6A4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105824-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC5 RECEPTOR AND TREATMENT OF CONDITIONS RELATED TO THIS RECEPTOR | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |