Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 7/20 | 0.42 |
| ▸ | DRD3 | P35462 | 7/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | MC1R | Q01726 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691855 | 0.92 | DRD2 (0.45) | OPRK1DRD2DRD3HTR1ASLC6A4 | |
| SCHEMBL13691857 | 0.92 | DRD2 (0.45) | OPRK1DRD2DRD3HTR1ASLC6A4 | |
| SCHEMBL13691861 | 0.90 | OPRK1 (0.55) | OPRK1SLC6A4RAB9ATACR2 | |
| SCHEMBL13189114 | 0.88 | PIN1 (0.40) | OPRK1DRD2DRD3HTR1ASLC6A4 | |
| SCHEMBL13189113 | 0.86 | UTS2R (0.38) | DRD2DRD3HTR1ASLC6A4ADRA1A | |
| SCHEMBL13189116 | 0.85 | UTS2R (0.39) | DRD2DRD3HTR1ANPC1DRD4 | |
| SCHEMBL13689546 | 0.84 | DRD2 (0.44) | DRD2DRD3HTR1ASLC6A4ADRA1A | |
| SCHEMBL13188483 | 0.84 | DRD2 (0.44) | DRD2DRD3HTR1ASLC6A4ADRA1A | |
| SCHEMBL13691779 | 0.84 | DRD2 (0.44) | DRD2DRD3HTR1ASLC6A4ADRA1A | |
| SCHEMBL19474295 | 0.84 | DRD2 (0.44) | DRD2DRD3HTR1ASLC6A4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105823-A1 | 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |