Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13602265 | 0.90 | PKM (0.63) | PKMLMNASMN1; SMN2MAPK1IDO1 | |
| SCHEMBL13689960 | 0.85 | GAA (0.56) | PKMLMNASMN1; SMN2ALOX15HTT | |
| SCHEMBL13689755 | 0.84 | UQCRB (0.53) | PKMALOX15HTTALDH1A1GPR27 | |
| SCHEMBL13690016 | 0.83 | RORC (0.53) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL28557447 | 0.82 | LMNA (0.64) | PKMLMNASMN1; SMN2MAPK1IDO1 | |
| SCHEMBL14567709 | 0.81 | LMNA (0.63) | PKMLMNASMN1; SMN2MAPK1IDO1 | |
| SCHEMBL13689995 | 0.80 | SMN1; SMN2 (0.58) | PKMLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL13689979 | 0.80 | PKM (0.60) | PKMLMNAALDH1A1GPR27 | |
| SCHEMBL13690049 | 0.78 | BDKRB1 (0.61) | SMN1; SMN2MAPK1HTTGAA | |
| SCHEMBL13690007 | 0.77 | ATM (0.58) | PKMLMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595399-B2 | Tyrosine derivatives | GENENTECH, INC. (US) | 2009-09-29 | — | — | US | disclosed |