Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690242 | 0.79 | KIF11 (0.44) | MAPTALDH1A1CYP3A4KIF11CA1 | |
| SCHEMBL21326414 | 0.78 | ALDH1A1 (0.36) | PTGS1MAPTALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL22700107 | 0.77 | MAPT (0.44) | PTGS1MAPTALDH1A1CYP3A4HTT | |
| SCHEMBL15947882 | 0.73 | MAPT (0.41) | MAPTALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL18598680 | 0.71 | MAPT (0.39) | MAPTALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL15391669 | 0.67 | MEN1 (0.38) | MAPTALDH1A1CYP3A4CYP2C9TDP1 | |
| SCHEMBL6313165 | 0.66 | MAPT (0.42) | PTGS1MAPTALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL14432373 | 0.63 | ACHE (0.48) | MAPTALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL3903543 | 0.62 | KIF11 (0.48) | MAPTALDH1A1CYP3A4TDP1KDM4E | |
| SCHEMBL11762144 | 0.61 | MAPT (0.48) | MAPTALDH1A1CYP3A4CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |