Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 7/20 | 0.38 |
| ▸ | CNR2 | P34972 | 7/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 3/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13502791 | 0.82 | HSD17B10 (0.41) | KDM4ETSHRHSD17B10CNR1CNR2 | |
| SCHEMBL17291913 | 0.82 | CNR2 (0.48) | KDM4ETSHRHSD17B10CNR1CNR2 | |
| SCHEMBL13502788 | 0.82 | SLC9A1 (0.41) | KDM4ETSHRHSD17B10CNR1CNR2 | |
| SCHEMBL28347009 | 0.80 | CNR2 (0.46) | KDM4ETSHRHSD17B10CNR1CNR2 | |
| SCHEMBL13502793 | 0.78 | PIM1 (0.46) | KDM4ETSHRHSD17B10CNR1CNR2 | |
| SCHEMBL1491875 | 0.78 | CNR2 (0.39) | KDM4ETSHRHSD17B10CNR1CNR2 | |
| SCHEMBL4050608 | 0.77 | CNR1 (0.52) | KDM4ETSHRHSD17B10CNR1CNR2 | |
| SCHEMBL8231479 | 0.77 | GLS (0.44) | KDM4ETSHRHSD17B10CNR1CNR2 | |
| SCHEMBL2809192 | 0.77 | ALDH1A1 (0.46) | KDM4ETSHRHSD17B10CNR1CNR2 | |
| SCHEMBL13502790 | 0.77 | GSK3B (0.47) | KDM4ETSHRHSD17B10HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |