Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189117 | 0.85 | GCGR (0.37) | TMEM97SIGMAR1OPRM1UTS2RKMT2A | |
| SCHEMBL13188836 | 0.82 | NPC1 (0.46) | TMEM97SIGMAR1OPRM1UTS2RKMT2A | |
| SCHEMBL13189111 | 0.80 | TMEM97 (0.44) | TMEM97SIGMAR1HDAC1HDAC4HDAC7 | |
| SCHEMBL13188826 | 0.79 | OPRM1 (0.49) | TMEM97SIGMAR1OPRM1KMT2AALOX5 | |
| SCHEMBL13189116 | 0.78 | UTS2R (0.39) | TMEM97SIGMAR1OPRM1UTS2RKMT2A | |
| SCHEMBL13188835 | 0.73 | OPRM1 (0.44) | TMEM97SIGMAR1OPRM1KMT2AHDAC3 | |
| SCHEMBL13689518 | 0.72 | OPRM1 (0.47) | TMEM97SIGMAR1OPRM1ALOX5HDAC3 | |
| SCHEMBL13691772 | 0.72 | OPRM1 (0.46) | TMEM97SIGMAR1OPRM1KMT2AHDAC3 | |
| SCHEMBL13691769 | 0.71 | OPRM1 (0.46) | TMEM97SIGMAR1OPRM1KMT2AHDAC3 | |
| SCHEMBL13189113 | 0.71 | UTS2R (0.38) | TMEM97SIGMAR1OPRM1UTS2RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105823-A1 | 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |