Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | DRD3 | P35462 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | DRD5 | P21918 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HAT1 | O14929 | 2/20 | 0.34 |
| ▸ | EP300 | Q09472 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189113 | 0.93 | UTS2R (0.38) | UTS2RDRD2DRD3NPC1TMEM97 | |
| SCHEMBL13691857 | 0.87 | DRD2 (0.45) | UTS2RDRD2DRD3DRD4MEN1 | |
| SCHEMBL13691855 | 0.87 | DRD2 (0.45) | UTS2RDRD2DRD3DRD4MEN1 | |
| SCHEMBL13189114 | 0.85 | PIN1 (0.40) | DRD2DRD3NPC1KMT2AHTR1A | |
| SCHEMBL13691859 | 0.85 | OPRK1 (0.43) | DRD2DRD3NPC1DRD4HTR1A | |
| SCHEMBL13188836 | 0.84 | NPC1 (0.46) | UTS2RDRD2DRD3NPC1TMEM97 | |
| SCHEMBL13691762 | 0.80 | NPC1 (0.44) | UTS2RDRD2DRD3NPC1TMEM97 | |
| SCHEMBL13691763 | 0.78 | TMEM97 (0.46) | UTS2RDRD2DRD3NPC1TMEM97 | |
| SCHEMBL13188483 | 0.78 | DRD2 (0.44) | UTS2RDRD2DRD3DRD4MEN1 | |
| SCHEMBL13691779 | 0.78 | DRD2 (0.44) | UTS2RDRD2DRD3DRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096854-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC3 AND/OR MC4 RECEPTORS AND TREATMENT OF CONDITIONS RELATED TO THESE RECEPTORS | MIMETICA PTY LTD (AU) | 2010-09-02 | — | — | WO | disclosed |