Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
| ▸ | DRD3 | P35462 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | DRD5 | P21918 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | GIPR | P48546 | 1/20 | 0.35 |
| ▸ | AHCY | P23526 | 1/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189116 | 0.93 | UTS2R (0.39) | UTS2RDRD2DRD3NPC1OPRM1 | |
| SCHEMBL13691857 | 0.88 | DRD2 (0.45) | UTS2RDRD2DRD3HTR1ADRD4 | |
| SCHEMBL13691855 | 0.88 | DRD2 (0.45) | UTS2RDRD2DRD3HTR1ADRD4 | |
| SCHEMBL13189114 | 0.86 | PIN1 (0.40) | DRD2DRD3NPC1HTR1ARAB9A | |
| SCHEMBL13691859 | 0.86 | OPRK1 (0.43) | DRD2DRD3NPC1HTR1ARAB9A | |
| SCHEMBL13189117 | 0.81 | GCGR (0.37) | UTS2RDRD2DRD3OPRM1TMEM97 | |
| SCHEMBL13691769 | 0.79 | OPRM1 (0.46) | DRD2DRD3NPC1OPRM1TMEM97 | |
| SCHEMBL13691853 | 0.79 | MAPT (0.44) | UTS2RDRD2DRD3SMN1; SMN2MEN1 | |
| SCHEMBL13188483 | 0.79 | DRD2 (0.44) | UTS2RDRD2DRD3HTR1ADRD4 | |
| SCHEMBL13691779 | 0.79 | DRD2 (0.44) | UTS2RDRD2DRD3HTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096854-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC3 AND/OR MC4 RECEPTORS AND TREATMENT OF CONDITIONS RELATED TO THESE RECEPTORS | MIMETICA PTY LTD (AU) | 2010-09-02 | — | — | WO | disclosed |