Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.43 |
| ▸ | MC5R | P33032 | 2/20 | 0.43 |
| ▸ | MC3R | P41968 | 2/20 | 0.43 |
| ▸ | MC1R | Q01726 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189115 | 0.88 | MC4R (0.44) | MC4RMC5RMC3RMC1RDRD3 | |
| SCHEMBL13691770 | 0.86 | MC4R (0.47) | MC4RMC5RMC3RMC1RDRD3 | |
| SCHEMBL13188833 | 0.82 | DRD2 (0.46) | MC4RMC5RMC3RMC1RDRD3 | |
| SCHEMBL13190970 | 0.79 | DRD2 (0.51) | MC4RMC5RMC3RMC1RDRD3 | |
| SCHEMBL13691792 | 0.78 | DRD2 (0.52) | MC4RMC5RMC3RMC1RDRD3 | |
| SCHEMBL13190971 | 0.76 | MC4R (0.48) | MC4RMC5RMC3RMC1RDRD3 | |
| SCHEMBL13691795 | 0.76 | DRD3 (0.47) | MC4RMC5RMC3RMC1RDRD3 | |
| SCHEMBL13691856 | 0.75 | DRD2 (0.47) | MC4RMC5RMC3RMC1RDRD3 | |
| SCHEMBL13691862 | 0.73 | UTS2R (0.43) | UTS2RLMNAGAAHTT | |
| SCHEMBL13689531 | 0.72 | DRD3 (0.52) | DRD3DRD2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105823-A1 | 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |