Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.47 |
| ▸ | MC5R | P33032 | 2/20 | 0.47 |
| ▸ | MC3R | P41968 | 2/20 | 0.47 |
| ▸ | MC1R | Q01726 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | DRD3 | P35462 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188833 | 0.95 | DRD2 (0.46) | MC4RMC5RMC3RMC1RDRD2 | |
| SCHEMBL13691795 | 0.90 | DRD3 (0.47) | MC4RMC5RMC3RMC1RDRD2 | |
| SCHEMBL13691865 | 0.86 | MC4R (0.43) | MC4RMC5RMC3RMC1RDRD2 | |
| SCHEMBL13190970 | 0.83 | DRD2 (0.51) | MC4RMC5RMC3RMC1RDRD2 | |
| SCHEMBL13189115 | 0.83 | MC4R (0.44) | MC4RMC5RMC3RMC1RDRD2 | |
| SCHEMBL13691792 | 0.82 | DRD2 (0.52) | MC4RMC5RMC3RMC1RDRD2 | |
| SCHEMBL13689522 | 0.82 | DRD2 (0.49) | MC4RMC5RMC3RMC1RDRD2 | |
| SCHEMBL13190971 | 0.81 | MC4R (0.48) | MC4RMC5RMC3RMC1RDRD2 | |
| SCHEMBL13691873 | 0.79 | THRB (0.46) | LMNAHTTUTS2RSMN1; SMN2 | |
| SCHEMBL13189119 | 0.79 | CYP3A4 (0.42) | GAALMNAHTTUTS2RSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105823-A1 | 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |