Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691767 | 0.89 | DRD3 (0.56) | DRD2DRD3KMT2AMEN1 | |
| SCHEMBL13689526 | 0.86 | SMYD2 (0.45) | SMYD2POLBMCHR1EPHX2DRD2 | |
| SCHEMBL13691766 | 0.76 | DRD3 (0.50) | DRD2DRD3KMT2AMEN1 | |
| SCHEMBL13691854 | 0.76 | OPRK1 (0.47) | SMYD2MCHR1EPHX2KMT2AMEN1 | |
| SCHEMBL13689521 | 0.75 | OPRK1 (0.51) | SMYD2EPHX2DRD2DRD3 | |
| SCHEMBL13691797 | 0.75 | DRD2 (0.54) | DRD2DRD3KMT2AMEN1 | |
| SCHEMBL13190972 | 0.72 | CXCR4 (0.46) | DRD2DRD3 | |
| SCHEMBL13691863 | 0.71 | TACR2 (0.49) | SMYD2 | |
| SCHEMBL13190976 | 0.69 | OPRK1 (0.52) | SMYD2EPHX2CACNA1G | |
| SCHEMBL13188825 | 0.69 | HDAC3 (0.44) | POLBEPHX2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105823-A1 | 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |