Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189115 | 0.86 | MC4R (0.44) | UTS2RLMNAGAAHTTNOS2 | |
| SCHEMBL13190967 | 0.86 | MAPT (0.47) | UTS2RLMNAGAAHTTNOS2 | |
| SCHEMBL13691865 | 0.73 | MC4R (0.43) | UTS2RLMNAGAAHTT | |
| SCHEMBL13689399 | 0.73 | LMNA (0.43) | LMNAHTTEGFRMMP1MMP2 | |
| SCHEMBL13689519 | 0.73 | LMNA (0.48) | UTS2RLMNAHTTEGFRL3MBTL1 | |
| SCHEMBL13691792 | 0.72 | DRD2 (0.52) | MAPTNLRP3MEN1KMT2ACYP1A2 | |
| SCHEMBL13190970 | 0.71 | DRD2 (0.51) | MAPTNLRP3SMN1; SMN2 | |
| SCHEMBL13691853 | 0.70 | MAPT (0.44) | UTS2RLMNAGAAHTTNOS2 | |
| SCHEMBL13190971 | 0.70 | MC4R (0.48) | UTS2RMAPTNLRP3MEN1KMT2A | |
| SCHEMBL13689400 | 0.69 | HDAC3 (0.44) | UTS2RLMNAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105823-A1 | 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |