Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 7/20 | 0.45 |
| ▸ | DRD2 | P14416 | 6/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | MC5R | P33032 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | MC1R | Q01726 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691766 | 0.77 | DRD3 (0.50) | DRD3DRD2SLC6A4ADRA1AMC4R | |
| SCHEMBL13691761 | 0.77 | DRD3 (0.43) | DRD3DRD2MC4RMC5RMC3R | |
| SCHEMBL13689520 | 0.76 | DRD3 (0.49) | DRD3DRD2SLC6A4ADRA1AMC4R | |
| SCHEMBL13689525 | 0.74 | DRD3 (0.51) | DRD3DRD2SLC6A4ADRA1AMC4R | |
| SCHEMBL13691854 | 0.73 | OPRK1 (0.47) | UTS2RKMT2A | |
| SCHEMBL13691800 | 0.73 | OPRK1 (0.49) | TP53KMT2A | |
| SCHEMBL13691855 | 0.73 | DRD2 (0.45) | DRD3DRD2SLC6A4ADRA1AUTS2R | |
| SCHEMBL13691767 | 0.73 | DRD3 (0.56) | DRD3DRD2SLC6A4ADRA1AMC4R | |
| SCHEMBL13691779 | 0.73 | DRD2 (0.44) | DRD3DRD2SLC6A4ADRA1AMC4R | |
| SCHEMBL13689546 | 0.73 | DRD2 (0.44) | DRD3DRD2SLC6A4ADRA1AMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105823-A1 | 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |