Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | CTSG | P08311 | 2/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.34 |
| ▸ | CMA1 | P23946 | 2/20 | 0.34 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 7/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10021105 | 0.82 | L3MBTL1 (0.38) | PRSS1CTSGCTRB1CMA1HTT | |
| SCHEMBL18660141 | 0.80 | CSNK1E (0.44) | PRSS1CTSGCTRB1CMA1GPR84 | |
| SCHEMBL13232167 | 0.79 | EPHX1 (0.38) | PRSS1CTSGCTRB1CMA1MLYCD | |
| SCHEMBL317660 | 0.79 | GPR84 (0.35) | PRSS1CTSGCTRB1CMA1MLYCD | |
| SCHEMBL10021100 | 0.77 | TSHR (0.39) | KIF11 | |
| SCHEMBL18660420 | 0.75 | ALDH1A1 (0.40) | KIF11PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL13232168 | 0.74 | CYP2D6 (0.39) | KIF11MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14402557 | 0.67 | AOC3 (0.41) | KIF11MEN1LMNAKMT2A | |
| SCHEMBL19234491 | 0.67 | KIF11 (0.42) | KIF11MEN1KMT2A | |
| SCHEMBL13849904 | 0.67 | AOC3 (0.41) | KIF11MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117378-A2 | THERAPEUTIC AMIDES | ALLERGAN, INC. (US) | 2009-09-24 | — | — | WO | disclosed |