Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 11/20 | 0.62 |
| ▸ | CES1 | P23141 | 11/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331128 | 0.91 | CES2 (0.56) | CES2CES1CYP2C19GAATSHR | |
| SCHEMBL25324982 | 0.91 | CES2 (0.56) | CES2CES1CYP2C19GAATSHR | |
| Methane SCHEMBL9572458 | 0.89 | CES2 (0.54) | CES2CES1CYP2C19GAATSHR | |
| SCHEMBL1372210 | 0.87 | CES2 (0.61) | CES2CES1CYP2C19GAATSHR | |
| SCHEMBL11416768 | 0.87 | CES2 (0.61) | CES2CES1CYP2C19GAATSHR | |
| SCHEMBL1370084 | 0.87 | CES2 (0.61) | CES2CES1CYP2C19GAATSHR | |
| SCHEMBL11424490 | 0.85 | CES2 (0.54) | CES2CES1CYP2C19GAAALDH1A1 | |
| SCHEMBL19669112 | 0.83 | TSHR (0.50) | CES2CES1CYP2C19GAATSHR | |
| SCHEMBL13860415 | 0.83 | CES1 (0.50) | CES2CES1CYP2C19GAATSHR | |
| SCHEMBL9000927 | 0.83 | TSHR (0.50) | CES2CES1CYP2C19GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022010-A1 | CHEMICAL AGENT DETECTION METHOD AND APPARATUS | CHEMMOTIF INC. (US) | 2010-01-28 | — | — | US | claimed |
| EP-1913399-A4 | CHEMICAL WARFARE AGENT (CWA) AND TOXIC INDUSTRIAL CHEMICAL (TIC) DETECTION BY DEGRADATION COMBINED WITH ACID-BASE INDICATOR DYES | CHEMMOTIF INC (US) | 2009-05-06 | — | — | EP | claimed |
| EP-1913399-A2 | CHEMICAL WARFARE AGENT (CWA) AND TOXIC INDUSTRIAL CHEMICAL (TIC) DETECTION BY DEGRADATION COMBINED WITH ACID-BASE INDICATOR DYES | Chemmotif, Inc. (US) | 2008-04-23 | — | — | EP | claimed |
| WO-2008018853-A2 | CHEMICAL WARFARE AGENT (CWA) AND TOXIC INDUSTRIAL CHEMICAL (TIC) DETECTION BY DEGRADATION COMBINED WITH ACID-BASE INDICATOR DYES | CHEMMOTIF, INC. (US) | 2008-02-14 | — | — | WO | claimed |
| JP-62201859-A | — | — | None | — | — | JP | disclosed |
| US-8273901-B2 | Process of forming a pyrrole compound | Nanyang Technical University (SG) | 2012-09-25 | — | — | US | disclosed |
| US-20110284394-A1 | Portable Electrochemical Multiphase Microreactor for Sensing Trace Chemical Vapors | The Board of Trustees of the University Illinois Office Technology (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110284394-A1 | Portable Electrochemical Multiphase Microreactor for Sensing Trace Chemical Vapors | The Board of Trustees of the University Illinois Office Technology (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110124881-A1 | PROCESS OF FORMING A PYRROLE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-05-26 | — | — | US | disclosed |
| US-20100022010-A1 | CHEMICAL AGENT DETECTION METHOD AND APPARATUS | CHEMMOTIF INC. (US) | 2010-01-28 | — | — | US | disclosed |
| EP-1913399-A4 | CHEMICAL WARFARE AGENT (CWA) AND TOXIC INDUSTRIAL CHEMICAL (TIC) DETECTION BY DEGRADATION COMBINED WITH ACID-BASE INDICATOR DYES | CHEMMOTIF INC (US) | 2009-05-06 | — | — | EP | disclosed |
| EP-1913399-A2 | CHEMICAL WARFARE AGENT (CWA) AND TOXIC INDUSTRIAL CHEMICAL (TIC) DETECTION BY DEGRADATION COMBINED WITH ACID-BASE INDICATOR DYES | Chemmotif, Inc. (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2008018853-A2 | CHEMICAL WARFARE AGENT (CWA) AND TOXIC INDUSTRIAL CHEMICAL (TIC) DETECTION BY DEGRADATION COMBINED WITH ACID-BASE INDICATOR DYES | CHEMMOTIF, INC. (US) | 2008-02-14 | — | — | WO | disclosed |
| JP-S62201859-A | NOVEL OXIME ESTER AND ITS SYNTHESIS | ASAHI CHEM IND CO LTD | 1987-09-05 | — | — | JP | disclosed |
| US-4459413-A | Process for preparing 5-imidazolyl ketones | AMERICAN CYANAMID COMPANY (US) | 1984-07-10 | — | — | US | disclosed |
| US-4395547-A | Process for preparing 1-substituted-6-n-propyl-8-methylimidazo[1,5-d]-as-triazin-4(3H)-ones | AMERICAN CYANAMID CO. (US) | 1983-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124881-A1 | PROCESS OF FORMING A PYRROLE COMPOUND | OXER1, OGDH, OPRD1 | CES2 1010/4885CES1 754/4885CYP2C19 726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.