Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | IAPP | P10997 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13693262 | 0.89 | CYP3A4 (0.57) | CYP3A4CYP1A2CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL28287006 | 0.83 | CYP19A1 (0.65) | CYP3A4CYP1A2CYP19A1APP | |
| SCHEMBL7725111 | 0.81 | PTPN1 (0.56) | HDAC1HDAC2 | |
| SCHEMBL26740416 | 0.81 | MAPT (0.56) | CYP3A4HDAC1HDAC2CYP1A2CYP2C19 | |
| SCHEMBL9680935 | 0.81 | RXRA (0.53) | CYP3A4IAPPHDAC1HDAC2CYP1A2 | |
| SCHEMBL3965463 | 0.80 | FFAR4 (0.59) | HDAC1HDAC2CYP19A1APP | |
| SCHEMBL1270315 | 0.80 | CYP3A4 (0.57) | CYP3A4CYP1A2CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL7528179 | 0.80 | LMNA (0.62) | CYP1A2 | |
| SCHEMBL1270074 | 0.79 | HDAC1 (0.55) | CYP3A4HDAC1HDAC2CYP1A2CYP2C8 | |
| SCHEMBL15255731 | 0.78 | HDAC1 (0.50) | HDAC1HDAC2CNR2APPLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589170-B1 | Synthesis of cyclic peptides | THE UNIVERSITY OF QUEENSLAND (AU) | 2009-09-15 | — | — | US | disclosed |