Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | IAPP | P10997 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358203 | 0.95 | RXRA (0.54) | RXRACNR1CNR2CYP1A2CYP3A4 | |
| SCHEMBL9358192 | 0.95 | RXRA (0.54) | RXRACNR1CNR2CYP1A2CYP3A4 | |
| SCHEMBL9680956 | 0.95 | RXRA (0.48) | RXRACNR1CNR2MAPTCYP1A2 | |
| SCHEMBL9680898 | 0.91 | MAPT (0.47) | RXRACNR1CNR2MAPTCYP1A2 | |
| SCHEMBL9681186 | 0.90 | CNR1 (0.44) | RXRACNR1CNR2MAPTCYP1A2 | |
| SCHEMBL8984878 | 0.90 | PPARG (0.49) | RXRACNR2MAPTPPARGPPARA | |
| SCHEMBL8984886 | 0.89 | MAPT (0.49) | MAPTCYP1A2CYP3A4CYP2C19HDAC1 | |
| SCHEMBL9362344 | 0.87 | HDAC1 (0.43) | RXRAMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9362113 | 0.86 | GABRA1 (0.53) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL8984897 | 0.86 | CNR1 (0.51) | CNR1CNR2ALOX5TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470832-A2 | Biphenyl 5,5'-bis-alkanoic acid derivatives, their production and use thereof | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-02-12 | — | — | EP | disclosed |