Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 6/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | FURIN | P09958 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1370010 | 0.99 | XDH (0.44) | XDHHDAC1HDAC2LTA4HBRD4 | |
| SCHEMBL1369225 | 0.91 | XDH (0.41) | XDHHDAC1HDAC2BRD4BRPF1 | |
| Hydrochloric Acid SCHEMBL1371823 | 0.90 | XDH (0.40) | XDHHDAC1HDAC2BRD4BRPF1 | |
| SCHEMBL2623138 | 0.86 | XDH (0.62) | XDHHDAC1HDAC2BRD4CA1 | |
| SCHEMBL13538979 | 0.85 | XDH (0.45) | XDHHDAC1HDAC2LTA4HBRD4 | |
| SCHEMBL7052321 | 0.85 | XDH (0.61) | XDHHDAC1HDAC2BRD4CA1 | |
| SCHEMBL5193809 | 0.85 | XDH (0.61) | XDHHDAC1HDAC2BRD4CA1 | |
| SCHEMBL27570010 | 0.82 | DEGS1 (0.47) | XDHHDAC1HDAC2BRD4BRPF1 | |
| SCHEMBL1371416 | 0.82 | XDH (0.41) | XDHHDAC1HDAC2BRD4AURKA | |
| SCHEMBL2826232 | 0.81 | HDAC1 (0.37) | XDHHDAC1HDAC2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288106-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universitaet Bonn Regina-Pacis-Weg 3 (DE) | 2011-11-24 | — | — | US | claimed |
| EP-2141166-A1 | Adenine receptor ligands | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2010-01-06 | — | — | EP | claimed |
| US-20110288106-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universitaet Bonn Regina-Pacis-Weg 3 (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110288106-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universitaet Bonn Regina-Pacis-Weg 3 (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110288106-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universitaet Bonn Regina-Pacis-Weg 3 (DE) | 2011-11-24 | — | — | US | disclosed |
| EP-2303884-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2011-04-06 | — | — | EP | disclosed |
| WO-2010000429-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2010-01-07 | — | — | WO | disclosed |
| WO-2010000429-A1 | ADENINE RECEPTOR LIGANDS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2010-01-07 | — | — | WO | disclosed |
| EP-2141166-A1 | Adenine receptor ligands | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141166-A1 | Adenine receptor ligands | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2010-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288106-A1 | ADENINE RECEPTOR LIGANDS | ADORA2A, ADORA1, ADORA3 | XDH 408/4885HDAC1 3321/4885HDAC2 3234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.