Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13695994 | 0.75 | MEN1 (0.34) | MEN1KMT2ANPC1TNKS2P2RX7 | |
| SCHEMBL17196547 | 0.73 | P2RX7 (0.46) | MEN1KMT2ANPC1TNKS2P2RX7 | |
| SCHEMBL18977333 | 0.71 | P2RX7 (0.43) | MEN1KMT2ANPC1TNKS2P2RX7 | |
| SCHEMBL14438929 | 0.67 | MEN1 (0.40) | MEN1KMT2ANPC1TNKS2ALDH1A1 | |
| SCHEMBL10815805 | 0.64 | ALDH1A1 (0.39) | MEN1KMT2ANPC1TNKS2ALDH1A1 | |
| SCHEMBL15604879 | 0.63 | — | — | |
| SCHEMBL1316915 | 0.63 | MEN1 (0.44) | MEN1KMT2ANPC1TNKS2ALDH1A1 | |
| SCHEMBL18125709 | 0.63 | CYP2C19 (0.45) | MEN1KMT2ANPC1TNKS2ALDH1A1 | |
| SCHEMBL11812669 | 0.63 | CYP2C19 (0.45) | MEN1KMT2ANPC1TNKS2ALDH1A1 | |
| SCHEMBL12787062 | 0.63 | NISCH (0.43) | MEN1KMT2ANPC1TNKS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239854-A1 | Tetracyclic compounds | MEDIVATION TECHNOLOGIES, INC. | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239854-A1 | Tetracyclic compounds | HTR2C, HTR3D, HTR5A | MEN1 2156/4885KMT2A 434/4885NPC1 3798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.