Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 12/20 | 0.47 |
| ▸ | F13A1 | P00488 | 2/20 | 0.44 |
| ▸ | TGM1 | P22735 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17685578 | 0.87 | TGM2 (0.49) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL17685582 | 0.83 | EGFR (0.50) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL29956621 | 0.82 | ALDH1A1 (0.44) | — | |
| SCHEMBL1369735 | 0.78 | TGM2 (0.56) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL12179308 | 0.76 | TGM2 (0.54) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL16634474 | 0.76 | TGM2 (0.57) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL17685580 | 0.75 | TGM2 (0.49) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL16653882 | 0.72 | TGM2 (0.59) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL12179321 | 0.70 | TGM2 (0.59) | TGM2PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL439369 | 0.70 | TGM2 (0.79) | TGM2F13A1TGM1LMNATGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |